"Tupot białych mew" to zaledwie początek problemów, jakie czekają Phila (Bradley Cooper), Stu (Ed Helms) i Alana (Zach Galifianakis), kiedy na kacu gigancie budzą się w jednym z hoteli Las Vegas. Kompletnie nie pamiętają, w jaki sposób w szafie znalazło się płaczące niemowlę, i czemu po apartamencie przechadza się kura, a w łazience leżakuje tygrys?! Na dodatek Doug (Justin Bartha) - przyszły pan młody, którego wieczór kawalerski wszyscy tak ochoczo świętowali, gdzieś przepadł...
Just two days before his marriage with Tracy Garner, Doug Billings, in the company of two friends: Phil Wenneck and Stu Price; and Tracy's eccentric brother, Alan, head out to party in Vegas. Driving his father's Mercedez, they rent a pricey villa at Caesar's and head for the rooftop to have a good time. Three of them later wake up with a hangover, unable to re-collect what exactly happened. With the villa in a wreck, they find that they have a baby in the closet; a grown tiger in the bathroom; Stu has a missing tooth and a hooker for a bride; and Doug is missing. Hilarious chaos results as the trio head out to re-trace their steps as well as try to locate Doug and bring him home in one piece before the wedding.
