Rick O’Connell (Brendan Fraser) powraca na ścieżkę przygody. Wraz z żoną Evelyn (Maria Bello) i jej bratem Jonathanem (John Hannah), muszą pomóc synowi Alexowi (Luke Ford), zmierzyć się z najgroźniejszym przeciwnikiem, z jakim kiedykolwiek mieli do czynienia.O'Connellowie muszą pokonać mumię bo w przeciwnym razie światem zawładnie złowroga i bezlitosna siła. Cesarz smok (Jet Li), skazany przez czarodziejkę (Michelle Yeoh) na wieczny niebyt, postanawia odzyskać dawne wpływy przy pomocy armii złożonej z 10 tysięcy wojowników z terakoty.
It's 1946 and Jack and Evie are now retired. They did a bit of espionage during World War II but have decided it's now the easy life for them. The only problem is that they are now quite bored so they jump at the chance to deliver a precious gem which the UK government is returning to China. Evie's brother Jonathan is now running a nightclub in Shanghai and they are surprised to also find their son Alex who is supposed to be at university but has on an archaeological dig with an old friend, Professor Roger Wilson. They soon find themselves involved in intrigue as a corrupt Chinese General needs the gem to resurrect Emperor Han and his army who have been dead for thousands of years.
